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Canadian Said to Have Had Key Role in Spread of AIDS

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Published by TiCam- 10-31-07
news Canadian Said to Have Had Key Role in Spread of AIDS

This article was published 10 years ago on The New York Times. A Canadian was ''Patient Zero,'' not a Haitian:
Canadian Said to Have Had Key Role in Spread of AIDS
AP
Published : October 7, 1987
LEAD: A forthcoming book identifies an airline steward from Montreal as playing a key role in the early spread of AIDS in North America.
A forthcoming book identifies an airline steward from Montreal as playing a key role in the early spread of AIDS in North America.
Randy Shilts, the author, says he uncovered the identity of the man, Gaetan Dugas, who died in 1984, from reading medical journals and interviewing health experts for his book, ''And the Band Played On: People, Politics and the AIDS Epidemic,'' to be published later this month by St. Martin's Press.
The book provides new details of the early spread of acquired immune deficiency syndrome in the late 1970's and early 1980's, and of what Mr. Shilts, who reports on AIDS for The San Francisco Chronicle, describes as the initial failure of society to comprehend and curb the deadly disease.
A slow Government response, lack of attention from the press and the initial failure of the gay community to accept changes in life style allowed AIDS to rage out of control in the early years of the disease, the book asserts.
Although charges of foot-dragging by scientists and Government health officials are not new, Mr. Shilts provides new details of these allegations in the 630-page book.
He writes that by the time America ''paid attention to the disease, it was too late to do anything about it.'' The epidemic ''was allowed to happen by an array of institutions, all of which failed to perform their appropriate tasks to safeguard the public health.''
He argues that if the news media had given more prominent coverage to the epidemic in its early stages, more Government funds and attention would have been directed against it.
Mr. Shilts, a homosexual, accuses many gay community advocates of treating AIDS originally as a ''public relations problem.'' Contracted in Europe
In retracing the early spread of AIDS among gay men, the book says scientists suspect Mr. Dugas brought the AIDS virus to this country after having contracted it in Europe through sexual contacts with Africans. While there is no way to determine whether he was the first person to bring the virus to North America, studies by Federal medical sleuths, previously reported without disclosing the man's name, have implicated him as a key actor in the initial spread of the virus among homosexual men in the late 1970's, before AIDS was identified.
Calling Mr. Dugas ''Patient Zero,'' researchers for the Federal Centers for Disease Control retraced his sexual activity as he traveled throughout North America, going from Canada to New York to Toronto to San Francisco on flight benefits, the book says.
Of the first 19 cases of AIDS reported in Los Angeles, four had sexual relations with Mr. Dugas and four others had sexual relations with one of his sexual partners. New York's first two known cases, in 1979, were his sexual partners.
At least 40 of the first 248 AIDS cases reported in the United States by April 1982 either had sexual relations with Mr. Dugas or one of his sex partners, says Mr. Shilts.
The book describes how the 28-year-old Mr. Dugas used his good looks and French-Canadian accent to lure handsome American men, even after he was diagnosed with AIDS in 1980.
In July 1981, Mr. Dugas told doctors trying to track down the origins of the disease that he had averaged 250 sexual liaisons every year for the last decade.
He refused to believe that his ''gay cancer,'' as he called it, could be spread sexually, telling a doctor, ''It's my right to do what I want with my body,'' according to the book.
Mr. Dugas died in March 1984, having survived four bouts of the form of pneumonia that often kills AIDS patients.
''At one time, Gaeten had been what every man wanted from gay life,'' Mr. Shilts writes. ''By the time he died, he had become what every gay man feared.''
Source: The New York Times
Canadian Said to Have Had Key Role in Spread of AIDS - New York Times=
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By bana2166 on 10-31-07, 02:40 PM
news Genetic study tracks AIDS virus journey to US

Genetic study tracks AIDS virus journey to US
New York, Oct 31: The United States' scientists have tracked the journey of deadly AIDS virus to the country, revealing that it arrived in the country from Africa via Haiti in 1960s.
A genetic analysis of 25-year-old frozen blood samples has outlined a new map of the AIDS virus journey out of Africa, showing that today's most widespread variety of HIV -- subtype B first emerged in Haiti in the 1960s and arrived in the United States a few years later.
The author of the study and an evolutionary biologist at the University of Arizona, Michael Worobey analysed five frozen blood samples collected in 1982 and 1983 from Haitian AIDS patients in Miami.
Mr Worobey and his colleagues compared the sequences of the two viral genes with viruses from around the world.
As a baseline, they used virus samples from Central Africa that are considered some of the earliest forms of the HIV.
The team found that the Haitian samples were genetically the most closely related to the African virus, indicating that they were among the earliest to branch off.
Mr Worobey concluded that the virus was brought to Haiti by workers who had gone to the Democratic Republic of Congo, formerly known as Zaire, after its independence in 1960. The virus appears to have been carried to the United States by Haitian immigrants between 1966 and 1972, according to the mutation timeline.
Researchers have debated for years whether the US epidemic came directly from Africa or through Haiti.
Dr Michael Gottlieb, one of the discoverers of acquired immune deficiency syndrome, said the analysis placed the virus in the United States nearly a decade earlier than previously believed, Los Angeles Times reported.
The analysis, published on Monday in the Proceedings of the National Academy of Sciences, focused on a variety of HIV known as subtype B, the most prevalent form in most countries outside Africa.
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By bana2166 on 10-31-07, 02:44 PM
news Traced: The Origins of the Aids Epidemic in America

Traced: The Origins of the Aids Epidemic in America
Posted on : 2007-10-30
An international team of scientists has revealed in the US National Academy of Sciences that the strain of the HIV virus which was the scourge of the United States and Europe in the 1970s and 1980s in all probability originated in the Caribbean island of Haiti. It was brought to American shores sometime around 1969 and thereafter spread to other countries. It took about twelve years for AIDS to be recognized in 1981.
The scientists had focused on a variety of HIV known as subtype B, which is prevalent most countries outside Africa, and found a 99.7% certainty that it had originated in Haiti.
In the course of their study they analyzed HIV DNA saved 25-years earlier in 1982-1983 from five people who were among the first recognized AIDS patients and who had all emigrated from Haiti to Miami.
As a baseline, they analyzed and used another 117 virus samples from Central Africa that are considered some of the earliest forms of the human immunodeficiency virus as well as samples from other parts of the world.
The team discovered that the Haitian samples and the African virus were the most closely related genetically pointing to the probability that they were among the earliest to branch.
They used this information to construct a family tree for the virus and they believe this allays any doubts of that the strain coming to the United States from Haiti. They believe it to be possible that one person was responsible for bringing the strain over somewhere around 1969.
The strain of the virus that became an epidemic in the US also spread to Canada, Europe, Australia, and Japan.
"Once the virus got to the US, then it just moved explosively around the world," Worobey said
Previous knowledge of the virus' migration has been only vaguely traced from its origin in Africa in the 1930s to when it was first detected in Los Angeles in 1981.
Assistant clinical professor of medicine at UCLA, Dr. Michael Gottlieb, who was one of the discoverers of acquired immune deficiency syndrome, stated that the study placed the virus in the United States nearly ten years earlier than had been previously believed.
"It's pretty clear evidence for Haiti as a steppingstone. The suggestion that the infection was further below our radar than I'd previously suspected is kind of unnerving," he is reported to have said.
The scientists hope that this knowledge will be instrumental in finding a cure for HIV and ultimately for AIDS.
One of the study's authors and evolutionary biologist, Michael Worobey from Tucson's University of Arizona and team now aim to trace the roots of the strain even further. He suspects that it most likely was brought to Haiti from the Democratic Republic of Congo, formerly Zaire, by Haitians working in Africa at that time.
The professor believes that understanding the genesis of this particular strain as well as those of other strains would allow scientists to accurately envisage its future modes of mutation.
Robert Garry, a microbiologist at Tulane University remarked, "The findings are significant,” and continued that they indicated "an important lineage of subtype B HIV was present in Haiti, which eventually spread elsewhere."
However he does not believe that a Haitian origin is the only explanation for subtype-B strains in the Americas, but thinks it quite possible that other B lineages made their appearance in the Americas before this and were most probably independent of the Haitian strain.
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